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Short term administration of gonadotropin-releasing hormone analog to a patient with a testosterone-secreting ovarian tumor.
- Source :
-
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 1987 Jun; Vol. 64 (6), pp. 1320-2. - Publication Year :
- 1987
-
Abstract
- A GnRH superagonist, buserelin, was administered for 16 days to a postmenopausal woman with a testosterone-secreting ovarian tumor. Serum gonadotropin levels decreased by more than 70%, and serum testosterone fell by more than 50%. This short term study demonstrates that in these uncommon tumors androgen secretion is gonadotropin sensitive, and suggests that GnRH analogs may have therapeutic value in such patients.
- Subjects :
- Administration, Intranasal
Chorionic Gonadotropin
Female
Follicle Stimulating Hormone blood
Humans
Leydig Cell Tumor blood
Luteinizing Hormone blood
Middle Aged
Ovarian Neoplasms blood
Testosterone blood
Buserelin therapeutic use
Leydig Cell Tumor metabolism
Ovarian Neoplasms metabolism
Pituitary Hormone-Releasing Hormones therapeutic use
Testosterone metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0021-972X
- Volume :
- 64
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The Journal of clinical endocrinology and metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 3106399
- Full Text :
- https://doi.org/10.1210/jcem-64-6-1320