Back to Search
Start Over
Detection of a new melanoma in a patient treated with fingolimod.
- Source :
-
BMJ case reports [BMJ Case Rep] 2019 Apr 29; Vol. 12 (4). Date of Electronic Publication: 2019 Apr 29. - Publication Year :
- 2019
-
Abstract
- In addition to the TRANSFORMS, FREEDOMS, INFORMS studies, very few publications have identified new cases of skin cancer in patients treated with fingolimod. Here, we present the case of a 52-year-old Caucasian patient with relapsing remitting multiple sclerosis for 19 years, with a phototype II with blue eyes, light brown hair, no personal or family history of melanoma and a low number of naevi (<10). She did not experience intense sun exposure in childhood as well as severe sunburn and did not practise sessions in ultraviolet cabins. This case is distinguished from other published cases, usually superficial spreading malignant melanoma by its unclassifiable histological character. The occurrence of skin cancers in patients with multiple sclerosis remains exceptional, but new cases have recently emerged requiring the strengthening of dermatological follow-up of such patients.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Female
Fingolimod Hydrochloride therapeutic use
Humans
Immunosuppressive Agents adverse effects
Immunosuppressive Agents therapeutic use
Melanoma pathology
Middle Aged
Multiple Sclerosis, Relapsing-Remitting complications
Nevus, Pigmented complications
Nevus, Pigmented pathology
Skin Neoplasms pathology
Treatment Outcome
Withholding Treatment
Fingolimod Hydrochloride adverse effects
Melanoma chemically induced
Multiple Sclerosis, Relapsing-Remitting drug therapy
Skin Neoplasms chemically induced
Subjects
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 12
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 31036735
- Full Text :
- https://doi.org/10.1136/bcr-2018-227951