Possible Mechanism of Hematocrit Elevation by Sodium Glucose Cotransporter 2 Inhibitors and Associated Beneficial Renal and Cardiovascular Effects.

Subjects

Subjects :

Adenosine Triphosphate metabolism
Cell Hypoxia drug effects
Diabetes Mellitus, Type 2 complications
Diabetes Mellitus, Type 2 drug therapy
Diabetic Cardiomyopathies drug therapy
Diabetic Cardiomyopathies prevention & control
Diabetic Nephropathies drug therapy
Diabetic Nephropathies prevention & control
Disease Progression
Diuresis drug effects
Erythropoietin biosynthesis
Erythropoietin genetics
Gene Expression Regulation drug effects
Glucose metabolism
Heart Failure etiology
Heart Failure prevention & control
Hemoglobins biosynthesis
Hemoglobins genetics
Humans
Kidney Tubules, Proximal metabolism
Renal Insufficiency, Chronic etiology
Renal Insufficiency, Chronic metabolism
Renal Insufficiency, Chronic prevention & control
Sodium-Glucose Transporter 2 Inhibitors therapeutic use
Sodium-Potassium-Exchanging ATPase metabolism
Sympathetic Nervous System drug effects
Sympathetic Nervous System physiopathology
Erythropoiesis drug effects
Heart drug effects
Hematocrit
Kidney drug effects
Sodium-Glucose Transporter 2 Inhibitors pharmacology

Details

Language :

English

ISSN :

1524-4539

Volume :

139

Issue :

17

Database :

MEDLINE

Journal :

Circulation

Publication Type :

Academic Journal

Accession number :

31009585

Full Text :

https://doi.org/10.1161/CIRCULATIONAHA.118.038881