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Acute lumbar polyradiculoneuropathy as early sign of methotrexate intrathecal neurotoxicity: Case report and literature review.
- Source :
-
Clinical case reports [Clin Case Rep] 2019 Feb 19; Vol. 7 (4), pp. 638-643. Date of Electronic Publication: 2019 Feb 19 (Print Publication: 2019). - Publication Year :
- 2019
-
Abstract
- Acute paraplegia after treatment with intrathecal methotrexate requires a complete spinal cord neuroimaging as well as electrodiagnostic examination. The absence of lumbosacral F waves motor responses without demyelinating findings may indicate early direct root toxicity. Early electromyography (EMG) screening could be a valuable tool for detecting peripheral neurotoxicity.<br />Competing Interests: None declared.
Details
- Language :
- English
- ISSN :
- 2050-0904
- Volume :
- 7
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Clinical case reports
- Publication Type :
- Report
- Accession number :
- 30997053
- Full Text :
- https://doi.org/10.1002/ccr3.2026