Polyclonal predominance of concurrently producing OXA-23 and OXA-58 carbapenem-resistant Acinetobacter baumannii strains in a pediatric intensive care unit.

Authors :: Karampatakis T
Tsergouli K
Politi L
Diamantopoulou G
Iosifidis E
Antachopoulos C
Karyoti A
Sdougka M
Tsakris A
Roilides E
Source :: Molecular biology reports [Mol Biol Rep] 2019 Jun; Vol. 46 (3), pp. 3497-3500. Date of Electronic Publication: 2019 Apr 12.
Publication Year :: 2019
Abstract: We report a predominance (64.7%) of polyclonal carbapenem-resistant Acinetobacter baumannii (CRAB) strains concurrently producing OXA-23 and OXA-58 carbapenemases in a pediatric intensive care unit in an endemic area. This is the first report of emergence of such double-OXA CRAB strains in a single unit worldwide.

Subjects :: Anti-Bacterial Agents pharmacology
Bacterial Proteins metabolism
Drug Resistance, Bacterial immunology
Humans
Intensive Care Units, Pediatric
Microbial Sensitivity Tests
beta-Lactamases metabolism
Acinetobacter baumannii drug effects
Acinetobacter baumannii metabolism
Carbapenems pharmacology

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