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Quantitative analysis of cochlear signal intensity on three-dimensional and contrast-enhanced fluid-attenuated inversion recovery images in patients with Meniere's disease: Correlation with the pure tone audiometry test.
- Source :
-
Journal of neuroradiology = Journal de neuroradiologie [J Neuroradiol] 2019 Sep; Vol. 46 (5), pp. 307-311. Date of Electronic Publication: 2019 Apr 03. - Publication Year :
- 2019
-
Abstract
- Purpose: The purpose of this study was to correlate the quantitative analysis of cochlear signal intensity (SI) on 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) and contrast-enhanced (CE) 3D-FLAIR images with results of the pure tone audiometry (PTA) test in patients with Meniere's disease (MD).<br />Materials and Methods: Over a 3-year period, 123 patients with MD underwent 3-Tesla (3 T) temporal magnetic resonance imaging (MRI), including 3D-FLAIR and CE-FLAIR sequences. The SI of membranous labyrinth of the cochlea in both ears of each patient was measured by drawing a region of interest (ROI) with a seed growing technique. The correlation between measured cochlear SIs on 3D-FLAIR and CE-FLAIR images, contrast enhancement index (CEI), and contrast enhancement ratio (CER) and clinical findings and pre- and post-treatment PTA results were assessed.<br />Results: Cochlear signal ratios of symptomatic ears on 3D-FLAIR and CE-FLAIR images were significantly higher than those of asymptomatic ears (P < 0.001). The area under the curve, from the receiver operating characteristic curve of cochlear SIs on 3D-FLAIR and CE-FLAIR images for discrimination between symptomatic and asymptomatic ears, was 0.729 and 0.728, respectively. Cochlear SIs on 3D-FLAIR and CE-FLAIR images were significantly correlated with patients' sex (P < 0.05 and P < 0.01, respectively), symptomatic ear (both P < 0.0001), and pre-treatment PTA (P < 0.0001 and P < 0.005, respectively), but were not significantly correlated with patients' age, post-treatment PTA or hearing threshold level at 0.5, 1.0, 2.0, or 4.0 kHz.<br />Conclusion: Quantitative analysis of cochlear SI on 3D-FLAIR and CE-FLAIR images may be a helpful diagnostic adjunct for MD, but may be of little value in predicting the prognosis of MD.<br /> (Copyright © 2019 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Adolescent
Adult
Aged
Audiometry, Pure-Tone
Child
Cochlea pathology
Cochlea physiopathology
Contrast Media
Female
Humans
Image Enhancement
Imaging, Three-Dimensional methods
Male
Meniere Disease pathology
Meniere Disease physiopathology
Middle Aged
Sensitivity and Specificity
Young Adult
Cochlea diagnostic imaging
Magnetic Resonance Imaging methods
Meniere Disease diagnostic imaging
Subjects
Details
- Language :
- English
- ISSN :
- 0150-9861
- Volume :
- 46
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of neuroradiology = Journal de neuroradiologie
- Publication Type :
- Academic Journal
- Accession number :
- 30953681
- Full Text :
- https://doi.org/10.1016/j.neurad.2019.03.010