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Toward a Universal Solution: Editing Compatibility into Pluripotent Stem Cells.
- Source :
-
Cell stem cell [Cell Stem Cell] 2019 Apr 04; Vol. 24 (4), pp. 508-510. - Publication Year :
- 2019
-
Abstract
- In this issue of Cell Stem Cell, Xu et al. (2019) demonstrate that editing iPSCs' major histocompatibility antigens may potentially provide a small set of universally compatible stem cell lines for therapies. However, these modifications may result in patient minor histocompatibility responses and deficiencies in their T cell response repertoire to infection and cancer.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1875-9777
- Volume :
- 24
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Cell stem cell
- Publication Type :
- Academic Journal
- Accession number :
- 30951658
- Full Text :
- https://doi.org/10.1016/j.stem.2019.03.003