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Progel Use is Not Associated with Decreased Incidence of Postoperative Air Leak after Nonanatomic Lung Surgery.
Progel Use is Not Associated with Decreased Incidence of Postoperative Air Leak after Nonanatomic Lung Surgery.
- Source :
-
The Permanente journal [Perm J] 2019; Vol. 23. - Publication Year :
- 2019
-
Abstract
- Context: Progel Pleural Air Leak Sealant (CR Bard, Warwick, RI) is a US Food and Drug Administration-approved hydrogel designed for application to surgical staple lines to prevent air leak after lung surgery. This product has demonstrated efficacy in reducing intraoperative air leaks compared with standard air leak closure methods. However, the impact on chest tube duration and length of hospital stay has not been reported.<br />Objective: To evaluate the effect on rates of postoperative air leak, chest tube duration, and hospital stay in surgical patients with and without use of Progel.<br />Design: Retrospective study of 176 patients aged 18 to 80 years who underwent video-assisted thoracoscopic wedge resections between 2014 and 2016. Eighty-four (48%) cases using Progel were included, as well as a representative sample of non-Progel cases (n = 92; 52%).<br />Main Outcome Measure: Presence of postoperative lung air leak.<br />Results: No difference existed between the Progel and non-Progel groups in the rate of postoperative air leak (20/84, 23.81% Progel; 16/92, 17.39% non-Progel; p = 0.33). The length of time patients had a chest tube was similar (23.5 vs 23 hours, p = 0.721), as was percentage of patients with a less than 2-day hospitalization (77.17% non-Progel vs 82.14% Progel, p = 0.414).<br />Conclusion: Our results suggest that Progel, used routinely in patients undergoing nonanatomic lung resection, does not have a significant impact on postoperative air leak, chest tube duration, or length of hospital stay. Further studies are warranted to evaluate the utility of Progel in reducing postoperative complications after thoracoscopic wedge resection in those treated for air leak or in the reduction of postoperative air leak in high-risk patients.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Chest Tubes statistics & numerical data
Female
Humans
Incidence
Length of Stay statistics & numerical data
Lung surgery
Male
Middle Aged
Retrospective Studies
Treatment Outcome
Young Adult
Hydrogel, Polyethylene Glycol Dimethacrylate therapeutic use
Postoperative Complications prevention & control
Thoracic Surgery, Video-Assisted
Subjects
Details
- Language :
- English
- ISSN :
- 1552-5775
- Volume :
- 23
- Database :
- MEDLINE
- Journal :
- The Permanente journal
- Publication Type :
- Academic Journal
- Accession number :
- 30939277
- Full Text :
- https://doi.org/10.7812/TPP/18-059