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Clinical presentations, management, and outcomes of acute esophageal necrosis: a systemic review.
- Source :
-
Expert review of gastroenterology & hepatology [Expert Rev Gastroenterol Hepatol] 2019 May; Vol. 13 (5), pp. 507-514. Date of Electronic Publication: 2019 Apr 16. - Publication Year :
- 2019
-
Abstract
- Background: To review all the reported literature on acute esophageal necrosis.<br />Research Methods: Databases were searched using the special Medical Subject Heading (MeSH) terms. All the available reported cases of acute esophageal necrosis were analyzed.<br />Results: A total of 154 cases were identified and 130 cases were analyzed. The mean age of presentation was 61 years, and 70% of cases were males. The most common presenting symptoms were hematemesis in 66%, shock in 36%, melena in 33%, abdominal or substernal pain in 28%. The most common comorbidities reported were diabetes in 38%, hypertension in 37%, alcohol abuse in 25%, and chronic kidney disease in 16%. On upper endoscopy, 51% had a distal disease, 36% had pan esophageal, and only 2% had a proximal disease. 84% of patients were treated with IV Proton Pump Inhibitors, 22% received transfusions, 23% got antibiotics for underlying sepsis, 14% also received sucralfate, and 4% required surgery for treatment. The mortality rate was 32%, while perforation was reported in 5% and stricture formation reported in 9% of patients.<br />Conclusions: Patients with acute esophageal necrosis can have a favorable outcome if treated appropriately.
Details
- Language :
- English
- ISSN :
- 1747-4132
- Volume :
- 13
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Expert review of gastroenterology & hepatology
- Publication Type :
- Academic Journal
- Accession number :
- 30933549
- Full Text :
- https://doi.org/10.1080/17474124.2019.1601555