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Palladium-Catalyzed Electrochemical C-H Bromination Using NH 4 Br as the Brominating Reagent.

Authors :
Yang QL
Wang XY
Wang TL
Yang X
Liu D
Tong X
Wu XY
Mei TS
Source :
Organic letters [Org Lett] 2019 Apr 19; Vol. 21 (8), pp. 2645-2649. Date of Electronic Publication: 2019 Mar 28.
Publication Year :
2019

Abstract

The palladium-catalyzed electrochemical C-H bromination of benzamide derivatives under divided cells is developed, in which NH <subscript>4</subscript> Br serves as a brominating reagent and electrolyte. The protocol avoids the use of chemical oxidants and provides an alternative method for the synthesis of aryl bromides.

Details

Language :
English
ISSN :
1523-7052
Volume :
21
Issue :
8
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
30920231
Full Text :
https://doi.org/10.1021/acs.orglett.9b00629