Back to Search
Start Over
A real-world, cross-sectional, community survey of symptoms and health-related quality of life of adults with acute myeloid leukemia.
- Source :
-
Future oncology (London, England) [Future Oncol] 2019 Jun; Vol. 15 (16), pp. 1895-1909. Date of Electronic Publication: 2019 Mar 26. - Publication Year :
- 2019
-
Abstract
- Aim: We used Adelphi Real World Disease-Specific Programme data to characterize adults with newly diagnosed or relapsed/refractory de novo acute myeloid leukemia (AML). Materials & methods: Community-practice hematologists/oncologists completed patient record forms for their regular AML patients. Patients were invited to complete patient self-completion forms including 3-Level EuroQol 5-Dimensions (EQ-5D-3L) and Functional Assessment of Cancer Therapy-Leukemia (FACT-Leu) questionnaires. Results: Physicians provided patient record forms for 389 patients (339 newly diagnosed, 50 relapsed/refractory); 68 patients completed patient self-completion forms. Mean EQ-5D visual-analog scale and index and FACT-General scores were significantly lower than US population norms (p < 0.0001); health-related quality of life (HRQoL) scores were generally lower than 11 other cancers. Conclusion: HRQoL impairment is grave in AML. Efforts are needed to improve HRQoL in affected patients.
- Subjects :
- Aged
Comorbidity
Cross-Sectional Studies
Disease Management
Female
Humans
Leukemia, Myeloid, Acute diagnosis
Leukemia, Myeloid, Acute therapy
Male
Middle Aged
Outcome Assessment, Health Care
Public Health Surveillance
Surveys and Questionnaires
United States epidemiology
Leukemia, Myeloid, Acute epidemiology
Quality of Life
Subjects
Details
- Language :
- English
- ISSN :
- 1744-8301
- Volume :
- 15
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- Future oncology (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 30912462
- Full Text :
- https://doi.org/10.2217/fon-2018-0842