Characterization of mcr-5 -Harboring Salmonella enterica subsp. enterica Serovar Typhimurium Isolates from Animal and Food Origin in Germany.

Authors :: Borowiak M
Hammerl JA
Deneke C
Fischer J
Szabo I
Malorny B
Source :: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2019 May 24; Vol. 63 (6). Date of Electronic Publication: 2019 May 24 (Print Publication: 2019).
Publication Year :: 2019
Abstract: We characterized eight mcr-5 -positive Salmonella enterica subsp. enterica serovar Typhimurium sequence type 34 (ST34) isolates obtained from pigs and meat in Germany. Five plasmid types were identified harboring mcr-5 on Tn 6452 or putative mobile insertion cassettes. The mobility of mcr-5 was confirmed by integration of Tn 6452 into the bacterial chromosomes of two strains and the detection of conjugative mcr-5 plasmids. The association with mobile genetic elements might further enhance mcr-5 distribution.<br /> (Copyright © 2019 American Society for Microbiology.)

Subjects :: Animals
Bacterial Proteins genetics
Drug Resistance, Bacterial
Germany
Humans
Microbial Sensitivity Tests
Plasmids genetics
Salmonella typhimurium drug effects
Salmonella typhimurium enzymology
Swine
Anti-Bacterial Agents pharmacology
Colistin pharmacology
Ethanolaminephosphotransferase genetics
Meat microbiology
Salmonella Infections microbiology
Salmonella typhimurium genetics

Full Text Access

Tools