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Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
- Source :
-
The Journal of antibiotics [J Antibiot (Tokyo)] 2019 Jun; Vol. 72 (6), pp. 469-475. Date of Electronic Publication: 2019 Mar 22. - Publication Year :
- 2019
-
Abstract
- A systematic study of the stability of a set of cephalosporins in mouse plasma reveals that cephalosporins lacking an acidic moiety at C-2 may be vulnerable to β-lactam cleavage in mouse plasma.
Details
- Language :
- English
- ISSN :
- 1881-1469
- Volume :
- 72
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The Journal of antibiotics
- Publication Type :
- Academic Journal
- Accession number :
- 30903100
- Full Text :
- https://doi.org/10.1038/s41429-019-0167-y