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Prebiotic Intake in Older Adults: Effects on Brain Function and Behavior.
- Source :
-
Current nutrition reports [Curr Nutr Rep] 2019 Jun; Vol. 8 (2), pp. 66-73. - Publication Year :
- 2019
-
Abstract
- Purpose of Review: This literature review summarizes the evidence for and against the impact of prebiotics on brain function and behavior in older adults.<br />Recent Findings: Current evidence generally supports the intake of prebiotics to increase beneficial gut bacteria concentrations. These bacteria appear to impact endocrine, immunologic, and neuronal communication along the gut-brain axis to alter brain function and behavior. Preliminary evidence in human studies consistently support prebiotics doses of ~ 5-10 g/d as safe to improve brain function (i.e., learning and working memory) and behavior (i.e., anxiety and mood). However, these studies are mainly of short duration (4-12 weeks) and limited to healthy, young, and middle-aged adults. More research is needed to identify a safe and effective dose, duration, and delivery method, particularly among diseased, older adults.
- Subjects :
- Affect drug effects
Aged
Animals
Anxiety drug therapy
Bacteria
Behavior physiology
Brain physiology
Gastrointestinal Tract microbiology
Humans
Learning drug effects
Learning physiology
Memory, Short-Term drug effects
Memory, Short-Term physiology
Middle Aged
Nervous System Physiological Phenomena
Behavior drug effects
Brain drug effects
Gastrointestinal Microbiome drug effects
Prebiotics administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 2161-3311
- Volume :
- 8
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Current nutrition reports
- Publication Type :
- Academic Journal
- Accession number :
- 30888666
- Full Text :
- https://doi.org/10.1007/s13668-019-0265-2