Back to Search
Start Over
Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis.
- Source :
-
PloS one [PLoS One] 2019 Mar 13; Vol. 14 (3), pp. e0212796. Date of Electronic Publication: 2019 Mar 13 (Print Publication: 2019). - Publication Year :
- 2019
-
Abstract
- While there is a burgeoning interest in the effects of nutrition on systemic inflammatory diseases, how dietary macronutrient balance impacts local chronic inflammatory diseases in the mouth has been largely overlooked. Here, we used the Geometric Framework for Nutrition to test how the amounts of dietary macronutrients and their interactions, as well as carbohydrate type (starch vs sucrose vs resistant starch) influenced periodontitis-associated alveolar bone height in mice. Increasing intake of carbohydrates reduced alveolar bone height, while dietary protein had no effect. Whether carbohydrate came from sugar or starch did not influence the extent of alveolar bone height. In summary, the amount of carbohydrate in the diet modulated periodontitis-associated alveolar bone height independent of the source of carbohydrates.<br />Competing Interests: The authors have declared that no competing interests exist.
- Subjects :
- Alveolar Bone Loss diagnostic imaging
Alveolar Bone Loss pathology
Alveolar Process diagnostic imaging
Alveolar Process pathology
Animals
Dietary Proteins administration & dosage
Dietary Proteins adverse effects
Dietary Sucrose administration & dosage
Disease Models, Animal
Humans
Male
Mice
Mice, Inbred C57BL
Organ Size
Starch administration & dosage
Alveolar Bone Loss etiology
Dietary Sucrose adverse effects
Feeding Behavior
Periodontitis etiology
Starch adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1932-6203
- Volume :
- 14
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- PloS one
- Publication Type :
- Academic Journal
- Accession number :
- 30865648
- Full Text :
- https://doi.org/10.1371/journal.pone.0212796