Loa loa Microfilariae in Skin Snips: Consequences for Onchocerciasis Monitoring and Evaluation in L. loa-Endemic Areas.

Authors :: Nana-Djeunga HC
Fossuo-Thotchum F
Pion SD
Chesnais CB
Kubofcik J
Mackenzie CD
Klion AD
Boussinesq M
Nutman TB
Kamgno J
Source :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2019 Oct 15; Vol. 69 (9), pp. 1628-1630.
Publication Year :: 2019
Abstract: The specificity of skin snips for onchocerciasis diagnoses is considered to be almost 100%. Our molecular methods revealed that microfilariae emerging from skin snips collected from highly microfilaremic Loa loa-infected individuals were largely misidentified as Onchocerca volvulus. This has important implications for onchocerciasis diagnostic testing in Loa-endemic areas.<br /> (© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.)

Subjects :: Adolescent
Adult
Aged
Aged, 80 and over
Animals
Child
Female
Humans
Loiasis metabolism
Male
Microfilariae metabolism
Middle Aged
Onchocerca volvulus pathogenicity
Onchocerciasis metabolism
Young Adult
Loa pathogenicity
Loiasis parasitology
Microfilariae parasitology
Onchocerciasis epidemiology

Language :: English
ISSN :: 1537-6591
Volume :: 69
Issue :: 9
Database :: MEDLINE
Journal :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Publication Type :: Academic Journal
Accession number :: 30861060
Full Text :: https://doi.org/10.1093/cid/ciz172

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