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Open-capsule intraocular lens to prevent posterior capsule opacification.
- Source :
-
Journal of cataract and refractive surgery [J Cataract Refract Surg] 2019 Jul; Vol. 45 (7), pp. 1007-1012. Date of Electronic Publication: 2019 Mar 08. - Publication Year :
- 2019
-
Abstract
- Purpose: To develop a single-piece open-capsule intraocular lens (IOL) that can be inserted through a small incision and that prevents posterior capsule opacification (PCO) by expanding the capsule and circulating aqueous humor into the capsular bag.<br />Setting: Department of Ophthalmology, Dokkyo Medical University, Tochigi, Japan.<br />Design: Experimental study.<br />Method: Using the same hydrophobic acrylic material as the NY-60 IOL, a prototype open-capsule IOL was constructed. The IOL has a single optic and 2 haptics, with a 2.8 mm high spacer and holes through which aqueous humor circulates into the capsular bag by separating the anterior capsule from the posterior capsule and expanding the capsule. The open-capsule IOL or NY-60 (as a control group) was inserted in rabbit eyes. Posterior capsule opacification development was evaluated by measuring the thickness of the cell layer at the center of the posterior capsule on histopathologic specimens and statistically comparing the thickness between the open-capsule IOL group and control group.<br />Results: The open-capsule IOL could be inserted through a 3.2 mm corneal incision using a D cartridge. The mean thickness of the cell layer at the center of the posterior capsule was 4.78 μm ± 2.61 (SD) in the open-capsule IOL group and 101.14 ± 25.19 μm in the control group and was significantly smaller in the open-capsule IOL group.<br />Conclusion: The prototype single-piece IOL could be implanted through a small incision and prevented PCO by expanding the lens capsule and circulating aqueous humor into the capsular bag.<br /> (Copyright © 2019. Published by Elsevier Inc.)
- Subjects :
- Animals
Capsule Opacification diagnosis
Disease Models, Animal
Female
Postoperative Complications diagnosis
Prosthesis Design
Rabbits
Acrylic Resins
Capsule Opacification prevention & control
Lens Implantation, Intraocular methods
Lenses, Intraocular
Posterior Capsule of the Lens pathology
Postoperative Complications prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1873-4502
- Volume :
- 45
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Journal of cataract and refractive surgery
- Publication Type :
- Academic Journal
- Accession number :
- 30853319
- Full Text :
- https://doi.org/10.1016/j.jcrs.2018.12.022