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Fluoroscopically Guided vs Landmark-Guided Sacroiliac Joint Injections: A Randomized Controlled Study.
- Source :
-
Mayo Clinic proceedings [Mayo Clin Proc] 2019 Apr; Vol. 94 (4), pp. 628-642. Date of Electronic Publication: 2019 Mar 08. - Publication Year :
- 2019
-
Abstract
- Objectives: To determine the prevalence of intra- and extra-articular sacroiliac joint (SIJ) pain, which injection is more beneficial, and whether fluoroscopy improves outcomes.<br />Patients and Methods: This patient- and evaluator-blinded comparative effectiveness study randomized 125 participants with SIJ pain from April 30, 2014, through December 12, 2017, to receive fluoroscopically guided injections into the joint capsule (group 1) or "blind" injections to the point of maximum tenderness using sham radiographs (group 2). The primary outcome was average pain on a 0 to 10 scale 1 month after injection. A positive outcome was defined as at least a 2-point decrease in average pain score coupled with positive (>3) satisfaction on a Likert scale from 1 to 5.<br />Results: For the primary outcome, no significant differences were observed between groups (mean ± SD change from baseline, -2.3±2.4 points in group 1 vs -1.7±2.3 points in group 2; 95% CI, -0.33 to 1.36 points for adjusted difference; P=.23), nor was there a difference in the proportions of positive blocks (61% vs 62%) or 1-month categorical outcome (48% vs 40% in groups 1 and 2, respectively; P=.33). At 3 months, the mean ± SD reductions in average pain (-1.8±2.1 vs -0.9 ± 2.0 points; 95% CI, 0.11 to 1.58 points for adjusted difference; P=.02) and worst pain (-2.2±2.5 vs -1.4±2.0 points; 95% CI, 0.01 to 1.66 points for adjusted difference; P=.049) were greater in group 1 than 2, with other outcome differences falling shy of statistical significance.<br />Conclusion: Although fluoroscopically guided injections provide greater intermediate-term benefit in some patients, these differences are modest and accompanied by large cost differences.<br />Trial Registration: clinicaltrials.gov Identifier: NCT02096653.<br /> (Copyright © 2018 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Anti-Inflammatory Agents administration & dosage
Double-Blind Method
Female
Fluoroscopy
Humans
Male
Middle Aged
Pain Measurement methods
Sacroiliac Joint diagnostic imaging
Sacroiliac Joint drug effects
Anesthetics, Local administration & dosage
Arthritis diagnostic imaging
Arthritis drug therapy
Injections, Intra-Articular methods
Low Back Pain drug therapy
Low Back Pain therapy
Sacroiliac Joint pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1942-5546
- Volume :
- 94
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Mayo Clinic proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 30853260
- Full Text :
- https://doi.org/10.1016/j.mayocp.2018.08.038