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Bronchial Artery Embolization for Hemoptysis in Primary Lung Cancer: A Retrospective Review of 84 Patients.
- Source :
-
Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2019 Mar; Vol. 30 (3), pp. 428-434. - Publication Year :
- 2019
-
Abstract
- Purpose: To evaluate the safety and efficacy of bronchial artery embolization (BAE) in patients with primary lung cancer-related hemoptysis and to identify factors associated with hemoptysis-free survival.<br />Methods: Data from 84 patients with primary lung cancer (non-small cell [n = 74] and small cell [n = 10]) who underwent BAE from 1997 to 2018 for the management of hemoptysis were retrospectively reviewed. Of these, 53 patients had stage IV lung cancer. The hemoptysis volume prior to initial BAE was trivial (blood-tinged sputum) in 21 patients, moderate (< 300 mL per 24 hours) in 34 patients, and massive (> 300 mL per 24 hours) in 29 patients.<br />Results: Technical success, defined as the ability to selectively embolize the abnormal vessel, was achieved in 83 patients (98.8%), and clinical success was achieved in 69 (82.1%) patients. Polyvinyl alcohol particles were used to embolize in 51 patients, gelfoam in 15 patients, and gelfoam plus microcoils in 17 patients. Hemoptysis recurred in 20 patients (23.8%) during follow-up. The median hemoptysis-free survival and overall survival periods were both 61 days. In the clinical-success and clinical-failure groups, the median overall survival period was 99 and 9 days, respectively (P < .001). In multivariable analysis, massive hemoptysis (P = .012) and cavitary lung mass (P = .019) were predictive factors for shortened hemoptysis-free survival.<br />Conclusions: BAE is a safe and effective approach to control hemoptysis, although the prognosis in primary lung cancer patients presenting with hemoptysis is generally poor. Massive hemoptysis and cavitary lung mass are significant predictors of shortened hemoptysis-free survival.<br /> (Copyright © 2018 SIR. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Aged
Carcinoma, Non-Small-Cell Lung diagnostic imaging
Carcinoma, Non-Small-Cell Lung pathology
Embolization, Therapeutic adverse effects
Female
Gelatin Sponge, Absorbable adverse effects
Hemoptysis etiology
Humans
Lung Neoplasms diagnostic imaging
Lung Neoplasms pathology
Male
Middle Aged
Neoplasm Staging
Polyvinyl Alcohol adverse effects
Progression-Free Survival
Recurrence
Republic of Korea
Retrospective Studies
Small Cell Lung Carcinoma diagnostic imaging
Small Cell Lung Carcinoma pathology
Time Factors
Tomography, X-Ray Computed
Bronchial Arteries
Carcinoma, Non-Small-Cell Lung complications
Embolization, Therapeutic methods
Gelatin Sponge, Absorbable administration & dosage
Hemoptysis therapy
Lung Neoplasms complications
Polyvinyl Alcohol administration & dosage
Small Cell Lung Carcinoma complications
Subjects
Details
- Language :
- English
- ISSN :
- 1535-7732
- Volume :
- 30
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of vascular and interventional radiology : JVIR
- Publication Type :
- Academic Journal
- Accession number :
- 30819488
- Full Text :
- https://doi.org/10.1016/j.jvir.2018.08.022