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Hodgkin's lymphoma, nephrotic syndrome, and echinococcosis cysts: an unusual association and literature review.

Authors :
Geylis M
Rosen GB
Danino D
Schreiber R
Hassan D
Nalbandyan K
Nahum A
Source :
Pediatric hematology and oncology [Pediatr Hematol Oncol] 2019 Feb; Vol. 36 (1), pp. 40-45. Date of Electronic Publication: 2019 Feb 20.
Publication Year :
2019

Abstract

We present a 5-year-old female with minimal change nephrotic syndrome (MCNS). Within several months, she became steroid-dependent with progression of edema and ascites. Imaging studies revealed abnormal solid mass and liver cysts and she was diagnosed with both abdominal Hodgkin's lymphoma (cHD) and large hepatic cystic echinococcosis (CE). Association between MCNS and cHL or with CE has been described in the literature in adults and rarely in the pediatric population. We report, for the first time, a simultaneous occurrence of all three: MCNS, cHL, and CE. Literature review and suggested pathophysiologic mechanisms underlying this phenomenon are presented.

Details

Language :
English
ISSN :
1521-0669
Volume :
36
Issue :
1
Database :
MEDLINE
Journal :
Pediatric hematology and oncology
Publication Type :
Academic Journal
Accession number :
30784346
Full Text :
https://doi.org/10.1080/08880018.2019.1571541