[Methanaphylaxis of urolithiasis. Part 1. Factors for increasing incidence of urolithiasis. Current theories of renal stone formation].

Urolithiasis is one of the most actively progressing diseases, a metabolic disorder that is strongly associated with a combination of genetic, lifestyle, and environmental factors. The first part presents current views on the factors triggering the formation of stones and the theory of stone formation. More specifically, the article discusses factors that contribute to the activation and inhibition of nucleation and aggregation of stone-forming substances.