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Dataset on the chemokine and cytokine responses of multi-cell cultures treated with Porphyromonas gingivalis hemagglutinin B.

Authors :
Abhyankar VP
Bates AM
Fischer CL
Johnson GK
Guthmiller JM
Progulske-Fox A
Brogden KA
Source :
Data in brief [Data Brief] 2018 Dec 31; Vol. 22, pp. 964-970. Date of Electronic Publication: 2018 Dec 31 (Print Publication: 2019).
Publication Year :
2018

Abstract

Chemokines and cytokines produced in gingival tissues exposed to microorganisms and microbial products in dental plaque lead to local inflammation and tissue damage seen in periodontal disease. Bates et al. 2018 [1] reported that Porphyromonas gingivalis hemagglutinin B (HagB)-induced matrix metalloproteinase (MMP) responses of single cell cultures containing dendritic cells, gingival epithelial (GE) keratinocytes, or T cells were significantly different from the MMP responses of these same cells grown in multi-cell cultures. Here we report the concentrations (pg/ml) of HagB-induced IL1α, IL6, IL8, IL12(p40), GM-CSF, MIP1α, MIP1β, RANTES, TNFα, and VEGF produced by dendritic cells, GE keratinocytes, or T cells in single cell cultures, two-cell cultures, or three-cell cultures.

Details

Language :
English
ISSN :
2352-3409
Volume :
22
Database :
MEDLINE
Journal :
Data in brief
Publication Type :
Academic Journal
Accession number :
30740479
Full Text :
https://doi.org/10.1016/j.dib.2018.12.087