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[Recent advances in analysis of endogenous toxic components in traditional Chinese medicines].

Authors :
Duan YP
Luo JY
Liu H
Shan LN
Yang SH
Yang MH
Source :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2018 Dec; Vol. 43 (24), pp. 4808-4816.
Publication Year :
2018

Abstract

Endogenous toxic components have become an important topic in the field of traditional Chinese medicines (TCMs). Since the endogenous toxic components in TCMs are often used as clinical effective components, the safety and effectiveness of endogenous toxic substances has become an important part of the research of TCMs. In this paper, the classification and evaluation criteria of toxic Chinese medicinal materials are described, and the analytical methods of endogenous components in TCMs are summarized and expounded base on with the techniques of chromatography, spectroscopy, immunoassay, and so on. On this basis, the problems in terms of endogenous toxic components are analyzed and discussed. This paper could provide ideas and methods for the evaluation of the validity and safety of TCMs containing endogenous toxic components.<br />Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.<br /> (Copyright© by the Chinese Pharmaceutical Association.)

Details

Language :
Chinese
ISSN :
1001-5302
Volume :
43
Issue :
24
Database :
MEDLINE
Journal :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Publication Type :
Academic Journal
Accession number :
30717524
Full Text :
https://doi.org/10.19540/j.cnki.cjcmm.20180703.009