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Effects of Congenital Heart Disease Treatmenton Quality of Life.
- Source :
-
The American journal of cardiology [Am J Cardiol] 2019 Apr 01; Vol. 123 (7), pp. 1163-1168. Date of Electronic Publication: 2019 Jan 08. - Publication Year :
- 2019
-
Abstract
- With rising survival rates of patients with congenital heart disease (CHD), functional health variables have become the key aspect in treatment evaluation. The effectiveness of various treatment options on the health-related quality of life (HRQoL) and the objectively measured exercise capacity as peak oxygen uptake (VO <subscript>2</subscript> peak) remains rather unclear and hence, its investigation is the primary aim of this study. Data from 1014 patients (≥14-years-old, various CHD) were retrospectively reviewed. The patients had completed at least twice the SF-36 questionnaire on HRQoL prior to a cardiopulmonary exercise test. Each patient was assigned to 1 of 4 treatment groups (i.e., surgery, catheter intervention, drug therapy, and surveillance) according to the received treatment between the baseline and the follow-up examination. After 4.0 ± 2.2 years of follow-up, patients with surgery and catheter intervention showed an increase in the physical summary score of HRQoL as compared to the other treatment groups (p <0.001). This effect remained also significant in a multivariable model accounting for anthropometric and baseline data. No significant differences in the mental summary score of HRQoL and the VO <subscript>2</subscript> peak were evident between the different treatment groups in the multivariable model. No significant correlation was found between the changes in HRQoL and VO <subscript>2</subscript> peak over time. In conclusion, despite insignificant changes in aerobic capacity, adolescents and adults with CHD report better physical HRQoL following surgery and catheter intervention compared to the other treatment options. HRQoL and exercise capacity need to be considered concurrently in the evaluation of adolescents and adults with CHD.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)
- Subjects :
- Adolescent
Adult
Aged
Exercise Test
Female
Follow-Up Studies
Heart Defects, Congenital physiopathology
Humans
Male
Middle Aged
Oxygen Consumption
Retrospective Studies
Surveys and Questionnaires
Young Adult
Exercise Therapy methods
Exercise Tolerance physiology
Heart Defects, Congenital psychology
Quality of Life
Subjects
Details
- Language :
- English
- ISSN :
- 1879-1913
- Volume :
- 123
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- The American journal of cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 30709599
- Full Text :
- https://doi.org/10.1016/j.amjcard.2018.12.048