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Bilateral cingulate cortices lesions in two autoantibodies directed against MOG (MOG-Ab)-positive patients.
- Source :
-
Multiple sclerosis and related disorders [Mult Scler Relat Disord] 2019 Apr; Vol. 29, pp. 108-110. Date of Electronic Publication: 2019 Jan 23. - Publication Year :
- 2019
-
Abstract
- There are no specific radiologic features in MOG-Ab (autoantibodies directed against myelin oligodendrocyte glycoprotein)-associated diseases. We present two MOG-Ab-positive patients with symmetrical lesions in the bilateral cingulate cortex of the frontal and parietal lobes. Those lesions showed hyperperfusion in acute phase and hypoperfusion in chronic phase on brain SPECT. In both patients, steroid therapy was effective in acute phase and for prevention of recurrence. High signal in the bilateral cingulate cortex on MR T2-weighted and FLAIR images might to be one of the unique findings considered MOG-Ab associated diseases.<br /> (Copyright © 2019. Published by Elsevier B.V.)
- Subjects :
- Acute Disease
Adult
Chronic Disease
Demyelinating Autoimmune Diseases, CNS diagnostic imaging
Demyelinating Autoimmune Diseases, CNS drug therapy
Demyelinating Autoimmune Diseases, CNS immunology
Female
Gyrus Cinguli diagnostic imaging
Humans
Magnetic Resonance Imaging
Male
Secondary Prevention
Tomography, Emission-Computed, Single-Photon
Autoantibodies immunology
Demyelinating Autoimmune Diseases, CNS pathology
Gyrus Cinguli pathology
Myelin-Oligodendrocyte Glycoprotein immunology
Steroids pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 2211-0356
- Volume :
- 29
- Database :
- MEDLINE
- Journal :
- Multiple sclerosis and related disorders
- Publication Type :
- Academic Journal
- Accession number :
- 30708307
- Full Text :
- https://doi.org/10.1016/j.msard.2019.01.035