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Impact of sarcopenia on clinical outcomes after radical gastrectomy for patients without nutritional risk.
- Source :
-
Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition] 2019 May; Vol. 61, pp. 61-66. Date of Electronic Publication: 2018 Oct 24. - Publication Year :
- 2019
-
Abstract
- Objective: The aim of this study was to investigate the prevalence of sarcopenia in patients without nutritional risk and the association between sarcopenia and postoperative outcomes after radical gastrectomy in these patients.<br />Method: We conducted a study of non-nutritional risk patients with gastric cancer who underwent gastrectomy from August 2014 to December 2017 in two centers. Nutritional Risk Screening 2002 (NRS 2002) was used to evaluate the nutritional risk. Patients who with NRS 2002 score <3 were classified as having no nutritional risk and were included in the study. Demographic and perioperative data were gathered. Sarcopenia was diagnosed based on the European Working Group on Sarcopenia in Older People criteria. Univariate and multivariate analysis were performed to determine the association between preoperative risk factors and postoperative complications.<br />Results: In all, 545 patients were included, in which the prevalence of sarcopenia and postoperative complications was 7.3% and 21.1%, respectively. Sarcopenia was significantly associated with higher age, lower body mass index, lower handgrip strength, lower usual walking speed, longer postoperative hospital length of stay, and higher costs. Multivariate analysis of prognostic factors revealed that sarcopenia was an independent predictor (odds ratio, 2.330; 95% confidence interval, 1.132-4.796; P = 0.022] for postoperative complications. Male sex, diabetes, and preoperative anemia also were risk factors for postoperative complications.<br />Conclusion: Sarcopenia was a significant independent risk factor for postoperative complications after gastrectomy in patients without nutritional risk. Preoperative assessment and management of sarcopenia should be helpful for improving clinical outcomes for patients without nutritional risk.<br /> (Copyright © 2018 Elsevier Inc. All rights reserved.)
- Subjects :
- Body Mass Index
Female
Hand Strength
Humans
Length of Stay
Male
Middle Aged
Postoperative Complications epidemiology
Preoperative Period
Prevalence
Risk Assessment
Risk Factors
Sarcopenia complications
Sarcopenia epidemiology
Stomach Neoplasms complications
Stomach Neoplasms physiopathology
Walking Speed
Gastrectomy adverse effects
Nutritional Status
Postoperative Complications etiology
Sarcopenia physiopathology
Stomach Neoplasms surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1873-1244
- Volume :
- 61
- Database :
- MEDLINE
- Journal :
- Nutrition (Burbank, Los Angeles County, Calif.)
- Publication Type :
- Academic Journal
- Accession number :
- 30703570
- Full Text :
- https://doi.org/10.1016/j.nut.2018.10.025