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The Content of ROS in Blood Lymphocytes of Healthy Individuals, Individuals Irradiated as a Result of Chernobyl Disaster and Patients with Prostate Cancer.

Authors :
Pelevina II
Aleshchenko AV
Antoshchina MM
Biryukov VA
Karpycheva AB
Karyakin OB
Krikunova LI
Ktitorova OV
Mkrtchyan LS
Nikonova MF
Oradovskaya IV
Paschenkova YG
Reva EV
Source :
Radiatsionnaia biologiia, radioecologiia [Radiats Biol Radioecol] 2016 Sep; Vol. 56 (5), pp. 469-474.
Publication Year :
2016

Abstract

The ROS concentration and proliferation activity (Ki67 expression.marker) have been studied in the periphery blood lymphocytes of Moscow and Obninsk citizens, donors, Chernobyl disaster liquidators, inhabitants of the region contaminated after Chernobyl disaster (Klincy) and individuals with prostate cancer. It was shown that ROS concentration in lymphocytes of the liquidators and residents of the polluted region was lowered. But in lymphocytes of patients with tumors the ROS content was higher in comparison with the control. The cell content with Ki67 expression in lymphocytes of the individuals resided in the polluted region and tumor patients was lowered.

Details

Language :
English; Russian
ISSN :
0869-8031
Volume :
56
Issue :
5
Database :
MEDLINE
Journal :
Radiatsionnaia biologiia, radioecologiia
Publication Type :
Academic Journal
Accession number :
30703305