Back to Search
Start Over
[Study of T lymphocyte subpopulations in patients with leprosy, using incubation with theophylline].
- Source :
-
Medicina cutanea ibero-latino-americana [Med Cutan Ibero Lat Am] 1988; Vol. 16 (5), pp. 397-401. - Publication Year :
- 1988
-
Abstract
- T cells and the theophylline resistant cells (the-r, helper cells) in peripheral blood of patients with different forms of leprosy were studied. Active lepromatous patients (LL+) showed a significant decrease in T lymphocytes and the-r cells. Nevertheless, in LL+ developing a reactional episode of erythema nodosum (LL-ENL) a restoration in the level of the-r cells was observed. It is concluded that in LL+ patients the depression of T cells and the-r cells represents an imbalance in the T-T cellular cooperation with a defective cellular immune response. On the other hand, the recovery of the-r cells in LL-ENL support the hypothesis of a cell mediated immune mechanism in the immunopathology of this reactional episode.
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0210-5187
- Volume :
- 16
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Medicina cutanea ibero-latino-americana
- Publication Type :
- Academic Journal
- Accession number :
- 3070196