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[Relationship of Executive Functions and Processing Speed with Cortical Gray Matter Morphometry in Healthy Adults and at The Early Stages of Schizophrenia].
- Source :
-
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova [Zh Vyssh Nerv Deiat Im I P Pavlova] 2016 Jul; Vol. 66 (4), pp. 448-457. - Publication Year :
- 2016
-
Abstract
- 13 male patients with schizophrenia and 18 age-matched healthy men underwent structural magnetic reso- nance imaging and completed the Stroop task which included the switching condition. As compared to con- trols, the patients showed slowing of color naming in the neutral condition and a reduction ofgray matter vol- ume and thickness in the frontal and temporal areas. In healthy subjects, the time of color naming was neg- atively correlated with gray matter volume in the left cuneus. In the schizophrenia group, there was a positive correlation between the time of color naming and cortical thickness in the middle and inferior frontal gyri of the right hemisphere. These results indicate a change in structural-functional relationships at the early stages of schizophrenia.
- Subjects :
- Adult
Brain Mapping
Case-Control Studies
Cerebrum diagnostic imaging
Cerebrum pathology
Frontal Lobe diagnostic imaging
Frontal Lobe pathology
Gray Matter diagnostic imaging
Gray Matter pathology
Humans
Magnetic Resonance Imaging
Male
Neuropsychological Tests
Occipital Lobe diagnostic imaging
Occipital Lobe pathology
Occipital Lobe physiopathology
Pattern Recognition, Visual
Reaction Time physiology
Schizophrenia diagnostic imaging
Schizophrenia pathology
Temporal Lobe diagnostic imaging
Temporal Lobe pathology
Temporal Lobe physiopathology
Cerebrum physiopathology
Color Perception
Executive Function
Frontal Lobe physiopathology
Gray Matter physiopathology
Schizophrenia physiopathology
Subjects
Details
- Language :
- Russian
- ISSN :
- 0044-4677
- Volume :
- 66
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova
- Publication Type :
- Academic Journal
- Accession number :
- 30695523