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[Status of antibiotic use in hospitalized children with community-acquired pneumonia in multiple regions of China].

Authors :
Wei W
Wang XF
Liu JP
Shen KL
Ma R
Cui ZZ
Deng L
Li YN
Jiang ZY
Xu H
Wang LN
Feng XC
Wu ZQ
Liu ZL
Huang Y
He CH
Liu H
Zhao X
Wang Z
Hao OM
Source :
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics [Zhongguo Dang Dai Er Ke Za Zhi] 2019 Jan; Vol. 21 (1), pp. 11-17.
Publication Year :
2019

Abstract

Objective: To investigate the use of antibiotics in children with community-acquired pneumonia (CAP) in multiple regions of China, and to provide a reference for CAP standard treatment and rational antibiotic use in children.<br />Methods: The medical data of 1 383 children with CAP who were hospitalized in the department of pediatrics in 10 grade A tertiary hospitals from 9 cities between April 14, 2014 and January 1, 2016 were reviewed, to analyze the status of antibiotic use in hospitalized children in North China, Northeast China, East China, and South China.<br />Results: The overall rate of antibiotic use in children with CAP was 89.08%, with 88.7% in North China, 95.5% in Northeast China, 83.3% in East China, and 86.6% in South China. The main types of antibiotics used were cephalosporins, macrolides, compound preparations of β-lactam antibiotics, polyphosphoric broad-spectrum antibiotics and other β-lactam antibiotics. The selection of antibiotics was generally rational, but antibiotics were still used in some patients with viral infection alone or a combined use of ≥2 kinds of antibiotics were noted in some patients with infection caused by one kind of pathogen. Irrational antibiotic use was observed in 131 children (10.63%).<br />Conclusions: There are high rates of antibiotic use and irrational use of antibiotics among children with CAP. Standard management of antibiotic use in children with CAP should be strengthened.

Details

Language :
Chinese
ISSN :
1008-8830
Volume :
21
Issue :
1
Database :
MEDLINE
Journal :
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Publication Type :
Academic Journal
Accession number :
30675857