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Advances in ovulation trigger strategies.
- Source :
-
Panminerva medica [Panminerva Med] 2019 Mar; Vol. 61 (1), pp. 42-51. - Publication Year :
- 2019
-
Abstract
- Ovulation trigger (OT) strategy is a cornerstone in modern patient-tailored in-vitro fertilization treatment, securing the optimal number of mature oocytes retrieved without compromising fertilization, embryo development and euploidy rates. Moreover, the OT strategy is taken into consideration before selecting fresh or frozen embryo transfer (freeze-all) to obtain optimal reproductive outcomes while maintaining a low risk of ovarian hyperstimulation syndrome. Several OT agents have been proposed, however, the most common agents used in modern IVF are human chorionic gonadotropin and gonadotropin-releasing hormone agonist. As no OT agent can be generally recommended for universal use, this review evaluates different OT strategies in different clinical scenarios, discussing both the biological plausibility and the clinical evidence.
- Subjects :
- Chorionic Gonadotropin therapeutic use
Cryopreservation
Embryo Transfer
Endometrium
Female
Fertility Agents, Female therapeutic use
Fertilization in Vitro
Humans
Kisspeptins chemistry
Oocytes metabolism
Reproductive Techniques, Assisted
Ovarian Hyperstimulation Syndrome prevention & control
Ovulation physiology
Ovulation Induction methods
Subjects
Details
- Language :
- English
- ISSN :
- 1827-1898
- Volume :
- 61
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Panminerva medica
- Publication Type :
- Academic Journal
- Accession number :
- 30674181
- Full Text :
- https://doi.org/10.23736/S0031-0808.18.03537-1