Back to Search
Start Over
Advanced stage melanoma therapies: Detailing the present and exploring the future.
- Source :
-
Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2019 Jan; Vol. 133, pp. 99-111. Date of Electronic Publication: 2018 Nov 15. - Publication Year :
- 2019
-
Abstract
- Metastatic melanoma therapies have proliferated over the last ten years. Prior to this, decades passed with only very few drugs available to offer our patients, and even then, those few drugs had minimal survival benefits. Many treatment options emerged over the last ten years with diverse mechanisms of action. Further, combination regimens have demonstrated superiority over monotherapy, especially for targeted agents. Each therapeutic combination possesses different advantages and side effect profiles. In this review, we outline the United States Food and Drug Administration-approved melanoma treatment agents and therapies currently in clinical development, focusing on combination approaches.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)
- Subjects :
- Antibodies, Monoclonal therapeutic use
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Disease Progression
Humans
Immunotherapy methods
Immunotherapy trends
Neoplasm Metastasis
Therapies, Investigational methods
United States
United States Food and Drug Administration
Combined Modality Therapy methods
Combined Modality Therapy trends
Melanoma pathology
Melanoma therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1879-0461
- Volume :
- 133
- Database :
- MEDLINE
- Journal :
- Critical reviews in oncology/hematology
- Publication Type :
- Academic Journal
- Accession number :
- 30661664
- Full Text :
- https://doi.org/10.1016/j.critrevonc.2018.11.002