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An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children.

Authors :
Sottile G
Ferrante G
Torregrossa M
Cibella F
Cilluffo G
Fasola S
Alessandro R
Seidita G
Viegi G
La Grutta S
Source :
Italian journal of pediatrics [Ital J Pediatr] 2019 Jan 15; Vol. 45 (1), pp. 16. Date of Electronic Publication: 2019 Jan 15.
Publication Year :
2019

Abstract

Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10-15 years. Overall, our findings reveal the importance of different genetic variants at 4p14, 16p12.1, 17q12, 6p12.2 and 17q21.1, identifying possible candidate genes responsible for susceptibility to asthma and rhino-conjunctivitis.

Details

Language :
English
ISSN :
1824-7288
Volume :
45
Issue :
1
Database :
MEDLINE
Journal :
Italian journal of pediatrics
Publication Type :
Editorial & Opinion
Accession number :
30646946
Full Text :
https://doi.org/10.1186/s13052-019-0603-4