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Pulmonary Tumor Thrombotic Microangiopathy Mimicking Inhalation Lung Injury.
- Source :
-
Internal medicine (Tokyo, Japan) [Intern Med] 2019 May 01; Vol. 58 (9), pp. 1311-1314. Date of Electronic Publication: 2019 Jan 10. - Publication Year :
- 2019
-
Abstract
- Pulmonary tumor thrombotic microangiopathy (PTTM) is a complication characterized by dyspnea, pulmonary hypertension, and occasionally sudden death. We encountered a man who developed PTTM and had an inhalation history of chemical herbicides and abnormal findings on chest computed tomography, mimicking chemical inhalation lung injury. He was diagnosed with PTTM with adenocarcinoma by a transbronchial lung biopsy and received chemotherapy and anticoagulant therapy. He survived for one month. An autopsy revealed primary gastric cancer with PTTM that can have a presentation similar to diffuse pulmonary diseases, including chemical inhalation lung injury. The examination of a biopsy specimen is crucial in such patients.
- Subjects :
- Adenocarcinoma diagnosis
Adenocarcinoma pathology
Aged
Autopsy
Biopsy
Burns, Inhalation diagnosis
Carcinoma, Signet Ring Cell diagnosis
Carcinoma, Signet Ring Cell secondary
Chlorine toxicity
Diagnosis, Differential
Dyspnea pathology
Fatal Outcome
Herbicides toxicity
Humans
Hypertension, Pulmonary complications
Lung Neoplasms diagnosis
Lung Neoplasms pathology
Lung Neoplasms secondary
Male
Neoplasms, Unknown Primary diagnosis
Neoplastic Cells, Circulating
Stomach Neoplasms diagnosis
Thrombotic Microangiopathies complications
Tomography, X-Ray Computed adverse effects
Acute Lung Injury diagnosis
Thrombotic Microangiopathies diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1349-7235
- Volume :
- 58
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Internal medicine (Tokyo, Japan)
- Publication Type :
- Academic Journal
- Accession number :
- 30626821
- Full Text :
- https://doi.org/10.2169/internalmedicine.1796-18