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Beating the Odds: A Full-Term Delivery After Liver Transplantation of a Pregnant Hyperthyroid Patient at 19 Weeks' Gestation for Propylthiouracil-Induced Acute Liver Failure.
- Source :
-
Transplantation proceedings [Transplant Proc] 2018 Dec; Vol. 50 (10), pp. 3995-3999. Date of Electronic Publication: 2018 Jun 30. - Publication Year :
- 2018
-
Abstract
- Liver transplantation (LT) for acute liver failure is an uncommon occurrence in the setting of pregnancy given the risk of fetal demise, and rarely is it undertaken with a viable fetus. Maternal hyperthyroidism increases fetal risk in the setting of LT, particularly in the setting of thyrotoxicosis. We report the first case of propylthiouracil-induced acute liver failure in a hyperthyroid patient in her second trimester resulting in LT. The multidisciplinary management led to a favorable outcome for the patient and the subsequent delivery of a healthy infant at 38-weeks' gestation.<br /> (Copyright © 2018 Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Female
Humans
Live Birth
Liver Failure, Acute chemically induced
Liver Failure, Acute surgery
Pregnancy
Pregnancy Complications surgery
Antithyroid Agents adverse effects
Graves Disease complications
Graves Disease drug therapy
Liver Transplantation methods
Pregnancy Complications chemically induced
Propylthiouracil adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2623
- Volume :
- 50
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Transplantation proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 30577302
- Full Text :
- https://doi.org/10.1016/j.transproceed.2018.06.046