Acute myeloid leukemia with eosinophilia after cyclin-dependent kinases 4/6 inhibitor treatment due to underlying clonal hematopoiesis of indeterminate potential.

Authors :: Anand K
Kumar P
Pingali SR
Pati D
Iyer SP
Source :: American journal of hematology [Am J Hematol] 2019 Mar; Vol. 94 (3), pp. E82-E85. Date of Electronic Publication: 2019 Jan 10.
Publication Year :: 2019

Subjects :: Adult
Animals
Antigens, Nuclear genetics
Antigens, Nuclear metabolism
Cell Cycle Proteins
Cyclin-Dependent Kinase 4 antagonists & inhibitors
Cyclin-Dependent Kinase 4 genetics
Cyclin-Dependent Kinase 4 metabolism
Cyclin-Dependent Kinase 6 antagonists & inhibitors
Cyclin-Dependent Kinase 6 genetics
Cyclin-Dependent Kinase 6 metabolism
DNA-Binding Proteins
Disease Models, Animal
Eosinophilia genetics
Eosinophilia metabolism
Eosinophilia pathology
Female
Hematopoiesis drug effects
Hematopoiesis genetics
Humans
Leukemia, Myeloid, Acute genetics
Leukemia, Myeloid, Acute metabolism
Leukemia, Myeloid, Acute pathology
Mice
Mutation
Nuclear Proteins deficiency
Nuclear Proteins genetics
Phosphoproteins deficiency
Phosphoproteins genetics
Aminopyridines adverse effects
Antineoplastic Agents adverse effects
Eosinophilia chemically induced
Granulocyte Colony-Stimulating Factor adverse effects
Leukemia, Myeloid, Acute chemically induced
Protein Kinase Inhibitors adverse effects
Purines adverse effects

Full Text Access

Tools