Mass Oral Azithromycin for Childhood Mortality: Timing of Death After Distribution in the MORDOR Trial.

Authors :: Porco TC
Hart J
Arzika AM
Weaver J
Kalua K
Mrango Z
Cotter SY
Stoller NE
O'Brien KS
Fry DM
Vanderschelden B
Oldenburg CE
West SK
Bailey RL
Keenan JD
Lietman TM
Source :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2019 May 30; Vol. 68 (12), pp. 2114-2116.
Publication Year :: 2019
Abstract: In a large community-randomized trial, biannual azithromycin distributions significantly reduced postneonatal childhood mortality in sub-Saharan African sites. Here, we present a prespecified secondary analysis showing that much of the protective effect was in the first 3 months postdistribution. Distributing more frequently than biannually could be considered if logistically feasible. Clinical Trials Registration. NCT02047981.<br /> (© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America.)

Subjects :: Child, Preschool
Female
Humans
Infant
Infant Mortality
Infant, Newborn
Male
Mass Drug Administration
Time Factors
Trachoma epidemiology
Anti-Bacterial Agents administration & dosage
Azithromycin administration & dosage
Child Mortality
Trachoma drug therapy
Trachoma mortality

Language :: English
ISSN :: 1537-6591
Volume :: 68
Issue :: 12
Database :: MEDLINE
Journal :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Publication Type :: Academic Journal
Accession number :: 30561577
Full Text :: https://doi.org/10.1093/cid/ciy973

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