Immunohistochemical analysis of tissue factor expression in gastric carcinoma: correlations with prognosis and survival.

Authors :: Toneto MG
Depaula PL
Debon L
Tertuliano B
Silva VD
Baldisseroto M
Fay AP
Carvalhal GF
Source :: Revista do Colegio Brasileiro de Cirurgioes [Rev Col Bras Cir] 2018 Nov 29; Vol. 45 (6), pp. e2030. Date of Electronic Publication: 2018 Nov 29.
Publication Year :: 2018
Abstract: Objective: to study the expression of the tissue factor (TF) and its correlation with prognosis and survival in patients with gastric carcinoma.<br />Methods: we measured the immunohistochemical expression of TF in 50 specimens of gastric adenocarcinomas from patients submitted to curative surgery. We then compared the intensity of its expression with clinical and pathological data, TNM staging, prognostic factors and survival.<br />Results: all tumors displayed TF expression; the intensity of TF expression was not associated with TNM stage, clinical or pathological variables or general survival.<br />Conclusion: TF has a high expression in gastric carcinoma, but that it is not useful as a prognostic marker.

Subjects :: Adenocarcinoma metabolism
Adenocarcinoma mortality
Aged
Brazil epidemiology
Female
Humans
Immunohistochemistry
Male
Middle Aged
Neoplasm Staging
Prognosis
Stomach Neoplasms metabolism
Stomach Neoplasms mortality
Adenocarcinoma pathology
Stomach Neoplasms pathology
Thromboplastin metabolism

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