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Utilization Rate of Helicobacter pylori Immunohistochemistry Is Not Associated With the Diagnostic Rate of Helicobacter pylori Infection.
- Source :
-
Applied immunohistochemistry & molecular morphology : AIMM [Appl Immunohistochem Mol Morphol] 2019 Oct; Vol. 27 (9), pp. 694-698. - Publication Year :
- 2019
-
Abstract
- Background: Utilization rates of immunohistochemistry (IHC) for the diagnosis of Helicobacter pylori infection may vary by laboratory and/or pathologists. IHC for H. pylori is not performed routinely in our practice. Instead, it is used in selected cases at the pathologists' discretion (and according to their specific criteria). The purpose of this study was to determine if IHC utilization rates correlated with rates of detecting H. pylori infection.<br />Materials and Methods: We searched our records and investigated all gastric biopsies for 1 calendar year. H. pylori diagnostic rate and IHC utilization rate was calculated for each pathologist.<br />Results: Overall, the rate of diagnosis was 12.1% and the IHC utilization rate was 45.2%. Individual pathologists had H. pylori diagnostic rates ranging from 3.6% to 34.1% (median: 11.1%) and IHC utilization ranging from 17.1% to 95.2% (median: 42.2%). The rate of detection of H. pylori infection among pathologists showed no significant correlation with rates of IHC utilization (Pearson coefficient=0.121).<br />Conclusions: Increasing use of IHC is not independently associated with the diagnostic rate of infection. Ultimately, if we assume that the case mix was similar for each pathologist, it suggests that more liberal criteria to order IHC does not result in more infections diagnosed.
- Subjects :
- Adult
Biopsy
Diagnostic Tests, Routine
Female
Helicobacter Infections epidemiology
Humans
Male
Middle Aged
Staining and Labeling
United States epidemiology
Gastric Mucosa pathology
Helicobacter Infections diagnosis
Helicobacter pylori physiology
Immunohistochemistry statistics & numerical data
Procedures and Techniques Utilization statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1533-4058
- Volume :
- 27
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Applied immunohistochemistry & molecular morphology : AIMM
- Publication Type :
- Academic Journal
- Accession number :
- 30499817
- Full Text :
- https://doi.org/10.1097/PAI.0000000000000680