Is the absence of alpha-helix 2 in the appendant structure region the major contributor to structural instability of human cystatin C?

Authors :: Zhou X
Lu X
Qin S
Xu L
Chong X
Liu J
Yan P
Sun R
Hurley IP
Jones GW
Wang Q
He J
Source :: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2019 Oct; Vol. 37 (17), pp. 4522-4527. Date of Electronic Publication: 2019 Jan 16.
Publication Year :: 2019

Subjects :: Amino Acid Sequence
Animals
Chickens
Humans
Hydrophobic and Hydrophilic Interactions
Molecular Dynamics Simulation
Protein Conformation, alpha-Helical
Protein Multimerization
Protein Stability
Recombinant Proteins chemistry
Structural Homology, Protein
Cystatin C chemistry

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