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Temporal trend of the proportion of patients presenting with advanced HIV in French Guiana: stuck on the asymptote?
Temporal trend of the proportion of patients presenting with advanced HIV in French Guiana: stuck on the asymptote?
- Source :
-
BMC research notes [BMC Res Notes] 2018 Nov 26; Vol. 11 (1), pp. 831. Date of Electronic Publication: 2018 Nov 26. - Publication Year :
- 2018
-
Abstract
- Objective: In French Guiana, the French territory with the most preoccupying HIV epidemic, there have been great efforts to intensify and diversify HIV testing strategies. The aim of the present study was to review the temporal trends of patients diagnosed with advanced HIV disease in French Guiana. Data trends from the HIV cohort of French Guiana between 1996 and 2016 were thus analyzed.<br />Results: The proportion of patients diagnosed with advanced disease did not decline over time. Males had lower CD4 counts at the time of diagnosis and there was a plateau for both males (around 40%) and females (around 25%) with no apparent reduction of the proportion of advanced disease. Older age groups and migrants presented more often with advanced disease. By contrast, the proportion of patients diagnosed with stage B and C disease declined over time and the CD4 count at antiretroviral initiation and the CD4 nadir increased over time. Despite some progress, the group of patients with advanced disease reached a plateau around 30% suggesting this particular group still has epidemiological importance in driving the epidemic and in fueling morbidity and mortality, and thus remains a challenge for testing strategies.
- Subjects :
- Adolescent
Adult
Anti-Retroviral Agents therapeutic use
CD4 Lymphocyte Count
CD4-Positive T-Lymphocytes cytology
Communicable Disease Control
Disease Progression
Emigrants and Immigrants
Epidemics
Female
French Guiana epidemiology
Humans
Male
Middle Aged
Time Factors
HIV Infections diagnosis
HIV Infections epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1756-0500
- Volume :
- 11
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC research notes
- Publication Type :
- Academic Journal
- Accession number :
- 30477588
- Full Text :
- https://doi.org/10.1186/s13104-018-3944-y