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Genitourinary tuberculosis in Taiwan: A 15-year experience at a teaching hospital.
- Source :
-
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2019 Apr; Vol. 52 (2), pp. 312-319. Date of Electronic Publication: 2018 Nov 09. - Publication Year :
- 2019
-
Abstract
- Background: Genitourinary tuberculosis (GUTB) is rare but fatal if not diagnosed early. The purpose of this study was to investigate the outcomes of GUTB in Taiwan.<br />Methods: We retrospectively reviewed medical records of 57 patients who were diagnosed as GUTB from January 2002 to December 2016, over a 15-year period. Demographic data and clinical manifestations were recorded for analysis.<br />Results: There were 37 males and 20 females with a median age of 71 years. Kidney (24.6%) was the most involved organ. Fever (56.1%) was the major presentation. Sixteen (28.1%) patients presented unfavorable outcome. Compared with the favorable outcome group, the unfavorable outcome group had more malignancy (p = 0.013), fever (p = 0.020), anemia (p = 0007), thrombocytopenia (p = 0.003), and hypoalbuminemia (p = 0.015). In a multivariate analysis, fever (odds ratio: 42.716, 95% confidence interval: 1.032-1767.569; p = 0.048) was identified as prognostic factors for unfavorable outcome.<br />Conclusion: GUTB is often in advanced stages with a high mortality in Taiwan. Establishing a diagnosis is difficult and requires thorough investigation. Fever is associated with unfavorable outcome.<br /> (Copyright © 2018. Published by Elsevier B.V.)
- Subjects :
- Adult
Aged
Aged, 80 and over
Anemia epidemiology
Antitubercular Agents pharmacology
Antitubercular Agents therapeutic use
Female
Fever epidemiology
Humans
Hypoalbuminemia epidemiology
Kaplan-Meier Estimate
Kidney Diseases epidemiology
Kidney Diseases microbiology
Logistic Models
Male
Microbial Sensitivity Tests
Middle Aged
Mortality
Multivariate Analysis
Neoplasms epidemiology
Neoplasms microbiology
Odds Ratio
Prognosis
Retrospective Studies
Risk Factors
Taiwan epidemiology
Thrombocytopenia epidemiology
Treatment Outcome
Urinary Tract surgery
Hospitals, Teaching
Tuberculosis, Urogenital drug therapy
Tuberculosis, Urogenital epidemiology
Tuberculosis, Urogenital pathology
Tuberculosis, Urogenital physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1995-9133
- Volume :
- 52
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
- Publication Type :
- Academic Journal
- Accession number :
- 30472096
- Full Text :
- https://doi.org/10.1016/j.jmii.2018.10.007