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Genitourinary tuberculosis in Taiwan: A 15-year experience at a teaching hospital.

Authors :
Huang TY
Hung CH
Hsu WH
Peng KT
Hung MS
Lai LJ
Chuang HJ
Tai WL
Ku YP
Wu TS
Source :
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2019 Apr; Vol. 52 (2), pp. 312-319. Date of Electronic Publication: 2018 Nov 09.
Publication Year :
2019

Abstract

Background: Genitourinary tuberculosis (GUTB) is rare but fatal if not diagnosed early. The purpose of this study was to investigate the outcomes of GUTB in Taiwan.<br />Methods: We retrospectively reviewed medical records of 57 patients who were diagnosed as GUTB from January 2002 to December 2016, over a 15-year period. Demographic data and clinical manifestations were recorded for analysis.<br />Results: There were 37 males and 20 females with a median age of 71 years. Kidney (24.6%) was the most involved organ. Fever (56.1%) was the major presentation. Sixteen (28.1%) patients presented unfavorable outcome. Compared with the favorable outcome group, the unfavorable outcome group had more malignancy (p = 0.013), fever (p = 0.020), anemia (p = 0007), thrombocytopenia (p = 0.003), and hypoalbuminemia (p = 0.015). In a multivariate analysis, fever (odds ratio: 42.716, 95% confidence interval: 1.032-1767.569; p = 0.048) was identified as prognostic factors for unfavorable outcome.<br />Conclusion: GUTB is often in advanced stages with a high mortality in Taiwan. Establishing a diagnosis is difficult and requires thorough investigation. Fever is associated with unfavorable outcome.<br /> (Copyright © 2018. Published by Elsevier B.V.)

Details

Language :
English
ISSN :
1995-9133
Volume :
52
Issue :
2
Database :
MEDLINE
Journal :
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Publication Type :
Academic Journal
Accession number :
30472096
Full Text :
https://doi.org/10.1016/j.jmii.2018.10.007