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Pediatric lupus nephritis.

Authors :
Pinheiro SVB
Dias RF
Fabiano RCG
Araujo SA
Silva ACSE
Source :
Jornal brasileiro de nefrologia [J Bras Nefrol] 2019 Apr-Jun; Vol. 41 (2), pp. 252-265. Date of Electronic Publication: 2018 Nov 14.
Publication Year :
2019

Abstract

Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options.

Details

Language :
English; Portuguese
ISSN :
2175-8239
Volume :
41
Issue :
2
Database :
MEDLINE
Journal :
Jornal brasileiro de nefrologia
Publication Type :
Academic Journal
Accession number :
30465590
Full Text :
https://doi.org/10.1590/2175-8239-JBN-2018-0097