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Clinical Validation of a Coronary Surgery Technique That Minimizes Aortic Manipulation.
- Source :
-
The Annals of thoracic surgery [Ann Thorac Surg] 2019 Apr; Vol. 107 (4), pp. 1166-1173. Date of Electronic Publication: 2018 Nov 13. - Publication Year :
- 2019
-
Abstract
- Background: To minimize aortic manipulation and maximize use of arterial conduits are aims of modern coronary surgery.<br />Methods: From March 2012 to October 2016, 890 consecutive patients with multivessel coronary disease underwent isolated coronary operations using both internal thoracic arteries (ITAs). In 205 (23%; mean age, 67.6 ± 9.2 years), the right ITA was proximally transected and used as a free graft, while its in situ stump was elongated with a saphenous vein graft. The new arteriovenous I conduit was directed to the inferolateral cardiac wall. Operative data and early outcomes of these patients (I group) were compared with the remaining 685 patients (control [C] group). Early and late outcomes were also compared in 184 pairs identified with propensity score matching.<br />Results: Between the I and C groups there was no significant difference in expected operative risk (European System for Cardiac Operative Risk Evaluation II, p = 0.28), although diseased ascending aorta (p < 0.0001) and critical preoperative state (p = 0.027) were more frequent in the I group. Despite a higher number of coronary anastomoses (mean, 4 ± 0.9 vs 3.7 ± 1, p < 0.0001), cardiopulmonary bypass time was shorter in the I group both in overall (86.7 ± 23.7 vs 105.7 ± 34.2 minutes, p < 0.0001) and matched series (86.8 ± 24.1 vs 108.8 ± 31.9 minutes, p < 0.0001). In-hospital mortality (1% vs 1.9%, p = 0.54) and the rates of postoperative complications were similar. During the follow-up period, no intergroup difference was found in matched patients in the nonparametric estimates of freedom from all-cause death (p = 0.39) and major adverse cardiac and cerebrovascular events (p = 0.44).<br />Conclusions: Surgery using this arteriovenous I conduit is safe, minimizes aortic manipulation, shortens cardiopulmonary bypass time, and aids complete revascularization.<br /> (Copyright © 2019 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Aged
Aged, 80 and over
Case-Control Studies
Coronary Angiography methods
Coronary Stenosis diagnostic imaging
Coronary Stenosis mortality
Female
Follow-Up Studies
Humans
Italy
Kaplan-Meier Estimate
Male
Middle Aged
Minimally Invasive Surgical Procedures methods
Retrospective Studies
Risk Assessment
Severity of Illness Index
Statistics, Nonparametric
Survival Analysis
Time Factors
Treatment Outcome
Vascular Patency physiology
Anastomotic Leak prevention & control
Coronary Artery Bypass methods
Coronary Stenosis surgery
Hospital Mortality
Internal Mammary-Coronary Artery Anastomosis methods
Subjects
Details
- Language :
- English
- ISSN :
- 1552-6259
- Volume :
- 107
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The Annals of thoracic surgery
- Publication Type :
- Academic Journal
- Accession number :
- 30444991
- Full Text :
- https://doi.org/10.1016/j.athoracsur.2018.09.063