A new protostane-type triterpenoid from Alisma plantago-aquatica subsp. orientale (Sam.) Sam.

Authors :: Li HM
Liu D
Dai WF
Chen XQ
Li RT
Source :: Natural product research [Nat Prod Res] 2019 Nov; Vol. 33 (21), pp. 3083-3088. Date of Electronic Publication: 2018 Nov 14.
Publication Year :: 2019
Abstract: A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W ( 1 ), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale . The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorelaxant activity and the inhibition on 11β -HSD1 of compound 1 were also evaluated, however, it didn't show remarkable effects.

Subjects :: 11-beta-Hydroxysteroid Dehydrogenase Type 1 antagonists & inhibitors
Humans
Molecular Structure
Rhizome chemistry
Spectrum Analysis
Triterpenes chemistry
Vasodilator Agents analysis
Alisma chemistry
Triterpenes isolation & purification

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