Precision oncology: separating the wheat from the chaff.

Authors :: Remon J
Dienstmann R
Source :: ESMO open [ESMO Open] 2018 Oct 30; Vol. 3 (6), pp. e000446. Date of Electronic Publication: 2018 Oct 30 (Print Publication: 2018).
Publication Year :: 2018
Abstract: Precision oncology based on next-generation sequencing (NGS) test is growing in daily clinical practice. However, the real impact of this strategy in patients' outcome on a large scale remains uncertain. In this review, we summarise existing literature on this topic, limitations for broad NGS implementation, bottlenecks in genomic variant interpretation and the role of molecular tumour boards.<br />Competing Interests: Competing interests: None declared.