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Halogenated Compounds from Corals: Chemical Diversity and Biological Activities.

Authors :
Zhang Y
Liu J
Shi D
Li Z
Source :
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2019; Vol. 19 (15), pp. 1204-1218.
Publication Year :
2019

Abstract

As important marine biological resources, corals produce a large amount of active organic compounds in their secondary metabolic processes, including numerous brominated, chlorinated, and iodinated compounds. These compounds, with novel structures and unique activities, guide the discovery and research of important lead compounds and novel biological mechanisms. Through a large number of literature surveys, this paper summarized a total of 145 halogenated secondary metabolites which were roughly divided into four major classes of terpenes, prostaglandins, steroids and alkaloids, and they were mainly isolated from ten coral families, Ellisellidae, Gorgoniidae, Briareidae, Plexauridae, Anthothelidae, Alcyoniidae, Clavularidae, Tubiporidae, Nephtheidae and Dendrophyllidae to the best of our knowledge. In addition, their organism species, structure composition and biological activity were also discussed in the form of a chart in this essay.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Details

Language :
English
ISSN :
1875-5607
Volume :
19
Issue :
15
Database :
MEDLINE
Journal :
Mini reviews in medicinal chemistry
Publication Type :
Academic Journal
Accession number :
30421673
Full Text :
https://doi.org/10.2174/1389557518666181113124015