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Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa.
- Source :
-
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2019 May 17; Vol. 68 (11), pp. 1932-1934. - Publication Year :
- 2019
-
Abstract
- Serious infections such as endocarditis due to extremely drug-resistance gram-negative bacteria are an increasing challenge. Here, we present successful adjunctive use of cefiderocol for a patient with persistently bacteremic healthcare-associated native aortic valve endocarditis due to an extended-spectrum beta-lactamase-positive Pseudomonas aeruginosa susceptible in vitro only to colistin, following failure of conventional therapeutic options.<br /> (© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America.)
- Subjects :
- Aged
Colistin pharmacology
Compassionate Use Trials
Endocarditis, Bacterial microbiology
Female
Humans
Microbial Sensitivity Tests
Pseudomonas Infections complications
Pseudomonas aeruginosa drug effects
Pseudomonas aeruginosa enzymology
Treatment Outcome
beta-Lactamases
Cefiderocol
Anti-Bacterial Agents therapeutic use
Aortic Valve microbiology
Cephalosporins therapeutic use
Drug Resistance, Multiple, Bacterial
Endocarditis, Bacterial drug therapy
Pseudomonas Infections drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1537-6591
- Volume :
- 68
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- Publication Type :
- Academic Journal
- Accession number :
- 30418554
- Full Text :
- https://doi.org/10.1093/cid/ciy963