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The association between Type 1 diabetes mellitus and periodontal diseases.

Authors :: Sun KT
Chen SC
Lin CL
Hsu JT
Chen IA
Wu IT
Palanisamy K
Shen TC
Li CY
Source :: Journal of the Formosan Medical Association = Taiwan yi zhi [J Formos Med Assoc] 2019 Jun; Vol. 118 (6), pp. 1047-1054. Date of Electronic Publication: 2018 Nov 01.
Publication Year :: 2019
Abstract: Background/purpose: Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease affecting oral health. Evidence shows possible association between T1DM and periodontal diseases (PDs). We conducted a nationwide population-based study in Taiwan, with a 14-year follow-up to investigate the risk of PDs in T1DM patients.<br />Methods: We used data from the National Health Insurance Research Database in Taiwan. The T1DM cohort was identified with newly diagnosed T1DM from 1998 to 2011. The non-T1DM cohort was frequency matched with the T1DM cohort. Participants comprised 4248 patients in the T1DM cohort and 16992 persons in the non-T1DM cohort.<br />Results: The T1DM patients showed an increased risk of PDs compared to non-T1DM individuals [adjusted hazard ratio (aHR) = 1.45]. T1DM patients who visited the emergency room more than twice per year had a higher aHR of 13.0 for developing PDs. The aHR for PDs was 13.2 in the T1DM patients who had been hospitalized more than twice per year.<br />Conclusion: T1DM patients are at higher risk of developing PDs than non-T1DM individuals. Our results further showed that the number of T1DM interventions; that is, annual emergency visits and hospitalizations were associated with increased the risk of developing PDs.<br /> (Copyright © 2018. Published by Elsevier B.V.)