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Dengue Virus IgM Serotyping by ELISA with Recombinant Mutant Envelope Proteins.

Authors :
Rockstroh A
Barzon L
Kumbukgolla W
Su HX
Lizarazo E
Vincenti-Gonzalez MF
Tami A
Ornelas AMM
Aguiar RS
Cadar D
Schmidt-Chanasit J
Ulbert S
Source :
Emerging infectious diseases [Emerg Infect Dis] 2019 Jan; Vol. 25 (1), pp. 1111-1115. Date of Electronic Publication: 2019 Jan 17.
Publication Year :
2019

Abstract

We developed an IgM-based ELISA that identifies the dengue virus serotype of recent infections. Dominant serotypes were detectable in 91.1% of samples from travelers and 86.5% of samples from residents of endemic regions; 97.1% corresponded to the serotype identified by PCR. This ELISA enables more accurate reporting of epidemiologic findings.

Details

Language :
English
ISSN :
1080-6059
Volume :
25
Issue :
1
Database :
MEDLINE
Journal :
Emerging infectious diseases
Publication Type :
Academic Journal
Accession number :
30387417
Full Text :
https://doi.org/10.3201/eid2501.180605